Compazine and Promethegan drug interactions - from FDA. Vestibular suppressant and antiemetic drugs are the mainstay of treatment of verto. Drug interactions are reported among people who take Compazine and Promethegan together. This review analyzes the effectiveness and drug interactions between.
Compazine, Compazine Spansules procorperazine dosing. One of the most universally distressing symptoms of illness is nausea, which may or may not be accompanied by vomiting. Medscape - Indication-specific dosing for Compazine, Compazine Spansules procorperazine, frequency-based adverse effects, comprehensive interactions.
Compazine Procorperazine Drug Information Side Effects. PO: Immediate-release, 5-10 mg q6-8hr; extended-release, 10 mg q12hr or 15 mg every morning Suppository: 25 mg q12hr IM: 5-10 mg q3-4hr; not to exceed 40 mg/day IV: 2.5-10 mg q3-4hr; not to exceed 10 mg/dose or 40 mg/day Prophylaxis IM: 5-10 mg administered 1-2 hours before induction of anesthesia; may be repeated once 30 minutes after initial dose IV: 5-10 mg administered 15-30 minutes before induction of anesthesia, repeated once before procedure if desired, or 20 mg/L administered 15-30 minutes before induction; not to exceed 30 mg/day Insomnia Restlessness (immediate restlessness or agitation may be treated with diphenhydramine 25 mg IV push) Dizziness Anxiety Euphoria Agitation Depression Weakness Headache Cerebral edema Poikilothermia Orthostatic hypotension (after IM injection) Tachycardia ECG changes Anorexia Dyspepsia Constipation Diarrhea Ileus Blood dyscrasia Galactorrhea Gynecomastia Ejaculatory disorder Lens opacities (with prolonged use) Photosensitivity Pruritus Akathisia Sedation Anticholinergic effects Weht gain Olomenorrhea or amenorrhea Erectile dysfunction Extrapyramidal symptoms (muscle stiffness, dystonia, parkinsonism, tardive dyskinesia) Neuroleptic malnant syndrome (infrequent but serious) Seizure Decreased gag reflex Confusion Hypotension Hypertension Leukopenia Agranulocytosis Cholestatic jaundice Photosensitivity reaction Priapism Hepatotoxicity Patients with dementia-related psychosis who are treated with antipsychotic drugs are at an increased risk of death, as shown in short-term controlled trials; the deaths appeared to be either cardiovascular (eg, heart failure, sudden death) or infectious (eg, pneumonia) in nature This drug is not approved for treatment of patients with dementia-related psychosis Documented hypersensitivity to phenothiazines Coma, severe CNS depression, concurrent use of large amounts of CNS depressants, poorly controlled seizure disorder, subcortical brain damage Postoperative management of nausea/vomiting following pediatric surgery Children Avoid using in children with suspected Reye syndrome Use caution in evere hypertension, severe cardiovascular disease Use with caution in glaucoma, prostatic hypertrophy, stenosing peptic ulcer disease, history of neuroleptic malnant syndrome, Parkinson disease, hypocalcemia, renal/hepatic impairment, history of severe reactions to insulin or electroconvulsive therapy, history of seizures, asthma, respiratory tract infections, cardiovascular disease, myelosuppression Blood dyscrasias including neutropenia, agranulocytosis, and leukopenia reported with use; discontinue therapy at first sn of blood dyscrasias Risk of extrapyramidal symptoms, neuroleptic malnant syndrome, hypotension (may be particularly severe in patients with pheochromocytoma or mitral insufficiency) Esophageal dysmotility/aspiration may occur; use with caution in patients at risk of pneumonia Depresses hypothalamic thermoregulatory mechanism; exposure to extreme temperatures may cause hypo- or hyperthermia May alter cardiac conduction; life-threatening arrhythmias reported with therapeutic doses May cause anticholinergic effects (constipation, xerostomia, urinary retention, blurred vision); use caution in patients with decreased gastrointestinal motility, paralytic ileus, urinary retention, BPH, xerostomia, visual problems May cause pmentary retinopathy and lenticular and corneal deposits, espcially in prolonged therapy May cause sedation and impair ability to perform tasks which require mental alertness, including operating heavy machinery Use associated with increased prolactin levels In case of severe hypotension, use norepinephrine or phenylepinephrine; do not use epinephrine or dopamine Do not crush extended-release product Avoid SC administration (may cause irritation) Antiemetic effect may obscure toxicity of chemotherapeutic drugs Use may be associated with neuroleptic malnant syndrome; monitor muscle ritidity, mental status changes, fever, autonomic instability May need anticholinergic antiparkinsonian agent to counter extrapyramidal symptoms May impair core body temperature regulation FDA warning regarding off-label use for dementia in elderly Antiemetic: Antidopaminergic effect, blocking dopamine receptors in the brain, blocking vagus nerve in GI tract Antipsychotic: Blocking mesolimbic dopamine receptors, and blocking alpha-adrenergic receptors (D1 and D2) in brain Solution: Compatible with most common solvents Additive: Amikacin, ascorbic acid injection, dexamethasone, dimenhydrinate, erythromycin, ethacrynate, lidocaine, nafcillin, penicillin G potassium (incompatible at hher concentrations), sodium bicarbonate, vitamins B and C Syringe (partial list): Atropine, corpromazine, cimetidine, diphenhydramine, fentanyl, glycopyrrolate, hydroxyzine, meperidine, metoclopramide, morphine sulfate (incompatible if phenol present)(? Learn about drug side effects and interactions for the drug Compazine Procorperazine.
Treatment Options for Nausea and Vomiting - Pharmacy Times Antinausea drugs are medicines that control nausea—a feeling of sickness or queasiness in the stomach with an urge to vomit. Drugs that control vomiting are ed antiemetic drugs. The needed relief, a prescription medication may be more appropriate. such as promethazine and procorperazine Compazine, as well as. Features and departments cover medication errors, drug interactions, patient.
Compazine phenergan interaction Dystonic reactions are reversible extrapyramidal effects that can occur after administration of a neuroleptic drug. Compazine phenergan interaction. have been shown to have a more fav. A Moderate Drug Interaction exists between Compazine and Phenergan.
Compazine phenergan drug interactions:
Rating: 95 / 100
Overall: 89 Rates